L’article sur WikiPédia en français

En anglais. Déclaration de projet.

Quelques remarques au fil des explications de la vidéo.

L’essais s’appelle Discovery. Quel rapport avec l’essai Solidarity de l’OMS ? (1)
Ce n’est pas très clair

Temps réel

L’annonce de la pandémie par l’OMS date du 9 janvier.
L’identification de la pandémie date de novembre 2019.
22 novembre -> 22 mars pour le premier patient.
Temps réel ?

Patients sans traitement

C’est la fameuse « 5ième branche » dont on parle discrètement.
Pour « faire de la science » il faut des patients témoins = des patients non-traités = des patients que l’on laisse mourir.

Médicaments « tolérés »

Au vu des scandales sanitaires on sait que les effets secondaires graves d’un médicament peuvent apparaître longtemps après la prescription.

Logistique

Là encore, il faut lire entre les lignes.
« Les hôpitaux sélectionnés sont ceux qui ont les moyens logistiques.« 
Traduction : s’il y a suffisamment d’ordinateurs suffisamment puissants, avec les bons informaticiens, c’est bon, sinon rien.

Notes

(1) L’article de l’OMS qui a « disparu » des écrans :

« Solidarity” is an international clinical trial to help find an effective treatment for COVID-19, launched by the World Health Organization and partners.

The Solidarity trial will compare four treatment options against standard of care, to assess their relative effectiveness against COVID-19. By enrolling patients in multiple countries, the Solidarity trial aims to rapidly discover whether any of the drugs slow disease progression or improve survival. Other drugs can be added based on emerging evidence.

Until there is sufficient evidence, WHO cautions against physicians and medical associations recommending or administering these unproven treatments to patients with COVID-19 or people self-medicating with them. WHO is concerned by reports of individuals self-medicating with chloroquine and causing themselves serious harm. WHO guidance on compassionate use can be found here.

The pressure COVID-19 puts on health systems means that WHO considered the need for speed and scale in the trial. While randomized clinical trials normally take years to design and conduct, the Solidarity trial will reduce the time taken by 80%.

Enrolling patients in one single randomized trial will help facilitate the rapid worldwide comparison of unproven treatments. This will overcome the risk of multiple small trials not generating the strong evidence needed to determine the relative effectiveness of potential treatments. 

Participation in Solidarity

The Solidarity trial provides simplified procedures to enable even overloaded hospitals to participate, with no paperwork required. As of March 27 2020, over 70 countries have already confirmed they will contribute to the trial, with many others in the process of joining.

The greater the number of participating countries, the faster results will be generated. WHO is facilitating access to thousands of treatment courses for the trial through donations from a number of manufacturers. WHO is also inviting developers and companies to collaborate on ensuring affordability and availability of the treatment options if they prove effective.

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